Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels

The cardiac intercalated disc harbors mechanical and electrical junctions as well as ion channel complexes mediating propagation of electrical impulses. Cardiac connexin43 (Cx43) co-localizes and interacts with several of the proteins located at intercalated discs in the ventricular myocardium. We h...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lübkemeier, Indra, Requardt, Robert Pascal, Lin, Xianming, Sasse, Philipp, Andrié, René, Schrickel, Jan Wilko, Chkourko, Halina, Bukauskas, Feliksas F., Kim, Jung-Sun, Frank, Marina, Malan, Daniela, Zhang, Jiong, Wirth, Angela, Dobrowolski, Radoslaw, Mohler, Peter J., Offermanns, Stefan, Fleischmann, Bernd K., Delmar, Mario, Willecke, Klaus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678986/
https://ncbi.nlm.nih.gov/pubmed/23558439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0348-y
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