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The Connexin40 A96S Mutation Causes Renin-Dependent Hypertension

Deletion of the gap-junction–forming protein connexin40 leads to renin-dependent hypertension in mice, but whether observed human variants in connexin40, such as A96S, promote hypertension is unknown. Here, we generated mice with the A96S variant in the mouse connexin40 gene. Although mice homozygou...

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書誌詳細
主要な著者: Lübkemeier, Indra, Machura, Katharina, Kurtz, Lisa, Neubauer, Björn, Dobrowolski, Radek, Schweda, Frank, Wagner, Charlotte, Willecke, Klaus, Kurtz, Armin
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103723/
https://ncbi.nlm.nih.gov/pubmed/21597036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010101047
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