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The Connexin40 A96S Mutation Causes Renin-Dependent Hypertension
Deletion of the gap-junction–forming protein connexin40 leads to renin-dependent hypertension in mice, but whether observed human variants in connexin40, such as A96S, promote hypertension is unknown. Here, we generated mice with the A96S variant in the mouse connexin40 gene. Although mice homozygou...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103723/ https://ncbi.nlm.nih.gov/pubmed/21597036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010101047 |
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