Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis

We characterize the allylic epoxyalcohols and their trihydroxy hydrolysis products generated from 9R- and 9S-hydroperoxy-octadecenoic acid (HPODE) under non-enzymatic conditions, reaction with hematin and subsequent acid hydrolysis, and enzymatic conditions, incubation with Beta vulgaris containing...

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Hauptverfasser: Thomas, Christopher P., Boeglin, William E., Garcia-Diaz, Yoel, O’Donnell, Valerie B., Brash, Alan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678760/
https://ncbi.nlm.nih.gov/pubmed/23352713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2013.01.002
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