MMP-7 Knock-In Corneal Fibroblast Cell Lines Secrete MMP-7 with Proteolytic Activity towards Collagen XVIII

PURPOSE: To determine whether matrix metalloproteinase-7 (MMP-7) that is stably overexpressed by mouse corneal fibroblast cell lines exhibits proteolytic activity against the NC1 fragment of collagen XVIII. METHODS: Corneal fibroblasts isolated from MMP-7 knockout (7ko) mice were subjected to SV40 T...

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Главные авторы: Yeh, Shu-I., Han, Kyu-Yeon, Sabri, Abdellah, Rosenblatt, Mark I., Azar, Dimitri T., Jain, Sandeep, Chang, Jin-Hong
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678734/
https://ncbi.nlm.nih.gov/pubmed/20795861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02713683.2010.494239
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