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HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption

Acute lung injury (ALI) results from loss of alveolar-capillary barrier integrity and the evolution of high-permeability pulmonary edema resulting in alveolar flooding and significant morbidity and mortality. HMGB1 is a late mediator of sepsis which uniquely participates in the evolution of sepsis a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wolfson, Rachel K., Chiang, Eddie T., Garcia, Joe G.N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678727/
https://ncbi.nlm.nih.gov/pubmed/21146549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2010.11.010
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