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Mutations in ZIC3 and ACVR2B are a common cause of heterotaxy and associated cardiovascular anomalies

BACKGROUND: Heterotaxy syndrome is caused by left-right asymmetry disturbances and is associated with abnormal lateralization of the abdominal and thoracic organs. The heart is frequently involved and the severity of the abnormality usually determines the outcome. METHODS: Direct sequence analysis o...

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Detalhes bibliográficos
Main Authors: Ma, Lijiang, Tierney, Elif Seda Selamet, Lee, Teresa, Lanzano, Patricia, Chung, Wendy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678527/
https://ncbi.nlm.nih.gov/pubmed/21864452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1047951111001181
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