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Use of 3-[(18)F]fluoropropanesulfonyl chloride as a prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides

3-[(18)F]Fluoropropanesulfonyl chloride, a recently proposed prosthetic agent for fluorine-18 labelling, was prepared in a two-step radiosynthesis via 3-[(18)F]fluoropropyl thiocyanate as an intermediate. Two benzenesulfonate-based radiolabelling precursors were prepared by various routes. Comparing...

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Detalhes bibliográficos
Main Authors: Löser, Reik, Fischer, Steffen, Hiller, Achim, Köckerling, Martin, Funke, Uta, Maisonial, Aurélie, Brust, Peter, Steinbach, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678395/
https://ncbi.nlm.nih.gov/pubmed/23766817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.115
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