Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation

Allergic airway inflammation is characterized by increased expression of pro-inflammatory mediators, inflammatory cell infiltration, mucus hypersecretion, and airway hyperresponsiveness, in parallel with oxidative DNA base and strand damage, whose etiological role is not understood. Our goal was to...

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Библиографические подробности
Главные авторы: Bacsi, Attila, Aguilera-Aguirre, Leopoldo, Szczesny, Bartosz, Radak, Zsolt, Hazra, Tapas K., Sur, Sanjiv, Ba, Xueqing, Boldogh, Istvan
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678389/
https://ncbi.nlm.nih.gov/pubmed/23127499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.002
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