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Molecular Basis of NF-κB Signaling

NF-κB (nuclear factor kappa B) family transcription factors are master regulators of immune and inflammatory processes in response to both injury and infection. In the latent state, NF-κBs are sequestered in the cytosol by their inhibitor IκB (inhibitor of NF-κB) proteins. Upon stimulations of innat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Napetschnig, Johanna, Wu, Hao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678348/
https://ncbi.nlm.nih.gov/pubmed/23495970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-083012-130338
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