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Ribosome profiling reveals resemblance between long non-coding RNAs and 5′ leaders of coding RNAs

Large-scale genomics and computational approaches have identified thousands of putative long non-coding RNAs (lncRNAs). It has been controversial, however, as to what fraction of these RNAs is truly non-coding. Here, we combine ribosome profiling with a machine-learning approach to validate lncRNAs...

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Detalhes bibliográficos
Main Authors: Chew, Guo-Liang, Pauli, Andrea, Rinn, John L., Regev, Aviv, Schier, Alexander F., Valen, Eivind
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678345/
https://ncbi.nlm.nih.gov/pubmed/23698349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.098343
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