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Distinct functional domains of the Abelson tyrosine kinase control axon guidance responses to Netrin and Slit to regulate the assembly of neural circuits
To develop a functional nervous system, axons must initially navigate through a complex environment, directed by guidance ligands and receptors. These receptors must link to intracellular signaling cascades to direct axon pathfinding decisions. The Abelson tyrosine kinase (Abl) plays a crucial role...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3678342/ https://ncbi.nlm.nih.gov/pubmed/23720041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.093831 |
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