The evolutionary dynamics of influenza A virus adaptation to mammalian hosts

Few questions on infectious disease are more important than understanding how and why avian influenza A viruses successfully emerge in mammalian populations, yet little is known about the rate and nature of the virus’ genetic adaptation in new hosts. Here, we measure, for the first time, the genomic...

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Main Authors: Bhatt, S., Lam, T. T., Lycett, S. J., Leigh Brown, A. J., Bowden, T. A., Holmes, E. C., Guan, Y., Wood, J. L. N., Brown, I. H., Kellam, P., Pybus, O. G., Brown, Ian, Brookes, Sharon, Germundsson, Anna, Cook, Alex, Williamson, Susanna, Essen, Stephen, Garcon, Fanny, Gunn, George, Sanchez, Manuel, Marques, Diogo, Wood, James, Tucker, Dan, McCrone, Ian, Gog, Julia, Saenz, Roberto, Staff, Meg, Murcia, Pablo, Barclay, Wendy, Donnelly, Christl, Elderfield, Ruth A., Kellam, Paul, Baillie, Greg, Coulter, Eve, Wieland, Barbara, Mastin, Alex, McCauley, John, Brown, Andy Leigh, Lycett, Sam, Woolhouse, Mark, Pybus, Oliver, Bhatt, Samir, Hayward, Andrew, Ishola, David, Archibald, Alan, Freeman, Tom, Charleston, Bryan, LeFevre, Eric, Bailey, Mick, Inman, Charlotte, Stokes, Chris, Chang, Kin Chow, Dunham, Stephen, White, Gavin, Nguyen-Van-Tam, Jonathan, Enstone, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678336/
https://ncbi.nlm.nih.gov/pubmed/23382435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0382
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