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DNA-mediated transfer of a human gene required for low-density lipoprotein receptor expression and for multiple Golgi processing pathways.

Transfection of a hamster cell mutant with human DNA corrected both the low-density lipoprotein receptor-deficient phenotype and the multiple glycosylation defects of the cells. Independently transfected colonies contained a small set of common human DNA fragments. These fragments may correspond to...

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Détails bibliographiques
Auteurs principaux: Kingsley, D M, Sege, R D, Kozarsky, K F, Krieger, M
Format: Artigo
Langue:Inglês
Publié: 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC367833/
https://ncbi.nlm.nih.gov/pubmed/3785210
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