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Use of a mutant cell line to study the kinetics and function of O-linked glycosylation of low density lipoprotein receptors.

A rapidly reversible defect in protein O-glycosylation exhibited by a line of mutant Chinese hamster ovary (CHO) cells was used to study the kinetics and function of O-glycosylation of the low density lipoprotein (LDL) receptor. The mutant line, genotype LDLD, cannot synthesize UDP-N-acetylgalactosa...

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Autors principals: Kozarsky, K, Kingsley, D, Krieger, M
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC280423/
https://ncbi.nlm.nih.gov/pubmed/3380796
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