Extended JAK Activation and Delayed STAT1 Dephosphorylation Contribute to the Distinct Signaling Profile of CNS Neurons Exposed to Interferon-Gamma

Although interferon-gamma (IFN-γ) plays a critical role in the noncytolytic elimination of many neurotropic viral infections, the signaling response to this cytokine has not been extensively characterized in primary CNS neurons. We previously demonstrated that the IFN-γ response at the signaling and...

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Autors principals: Podolsky, Michael A., Solomos, Andreas C., Durso, Lisa C., Evans, Stephanie M., Rall, Glenn F., Rose, R. Wesley
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678282/
https://ncbi.nlm.nih.gov/pubmed/22769061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2012.06.006
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