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Noncytolytic Clearance of Sindbis Virus Infection from Neurons by Gamma Interferon Is Dependent on Jak/Stat Signaling

The alphavirus Sindbis virus (SINV) causes encephalomyelitis in mice by infecting neurons of the brain and spinal cord. The outcome is age dependent. Young animals develop fatal disease, while older animals recover from infection. Recovery requires noncytolytic clearance of SINV from neurons, and ga...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Burdeinick-Kerr, Rebeca, Govindarajan, Dhanasekaran, Griffin, Diane E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663278/
https://ncbi.nlm.nih.gov/pubmed/19176616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02381-08
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