Mechanisms of bone fragility in a glucocorticoid-treated mouse model of rheumatoid arthritis – implications for insufficiency fracture risk

OBJECTIVE: Glucocorticoid (GC) therapy is associated with increased fracture risk in rheumatoid arthritis (RA) patients. To elucidate the cause of this increased risk, we examined the effects of chronic inflammatory-erosive arthritis and GC treatment on bone quality, structure, and biomechanical pro...

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Autori principali: Takahata, Masahiko, Maher, Jason R., Juneja, Subhash C., Inzana, Jason, Xing, Lianping, Schwarz, Edward M., Berger, Andrew J., Awad, Hani A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678247/
https://ncbi.nlm.nih.gov/pubmed/22832945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34639
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