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Oncogene amplification during tumorigenesis of established rat fibroblasts reversibly transformed by activated human ras oncogenes.

Normal rat fibroblasts of the established cell line Rat 4 were cotransformed with activated human ras oncogenes and with a cloned chicken thymidine kinase (tk) gene. Linkage between tk and ras genes allowed the isolation of oncogene deletion revertants and of cell clones showing varying degrees of m...

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Publicat a:Mol Cell Biol
Autors principals: Winter, E, Perucho, M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3785202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.7.2562-2570.1986
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