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Single KATP channel opening in response to stimulation of AMPA/kainate receptors is mediated by Na(+) accumulation and submembrane ATP and ADP changes

Excessive stimulation of glutamatergic receptors (GluRs) can overexcite neurons. This can be dampened by KATP channels linking metabolic and neuronal activities, but the cross-talk has not yet been examined on the single channel level. In the brainstem and hippocampal neurons, GluR agonists augmente...

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Autores principales: Mollajew, R, Toloe, J, Mironov, S L
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678045/
https://ncbi.nlm.nih.gov/pubmed/23507878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.248369
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