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Inverse Agonist and Pharmacochaperone Properties of MK-0524 on the Prostanoid DP1 Receptor
Prostaglandin D(2) (PGD(2)) acts through two G protein-coupled receptors (GPCRs), the prostanoid DP receptor and CRTH2 also known as DP1 and DP2, respectively. Several previously characterized GPCR antagonists are now classified as inverse agonists and a number of GPCR ligands are known to display p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3677937/ https://ncbi.nlm.nih.gov/pubmed/23762421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065767 |
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