Enhancing the Power of Genetic Association Studies through the Use of Silver Standard Cases Derived from Electronic Medical Records

The feasibility of using imperfectly phenotyped “silver standard” samples identified from electronic medical record diagnoses is considered in genetic association studies when these samples might be combined with an existing set of samples phenotyped with a gold standard technique. An analytic expre...

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Main Authors: McDavid, Andrew, Crane, Paul K., Newton, Katherine M., Crosslin, David R., McCormick, Wayne, Weston, Noah, Ehrlich, Kelly, Hart, Eugene, Harrison, Robert, Kukull, Walter A., Rottscheit, Carla, Peissig, Peggy, Stefanski, Elisha, McCarty, Catherine A., Zuvich, Rebecca Lynn, Ritchie, Marylyn D., Haines, Jonathan L., Denny, Joshua C., Schellenberg, Gerard D., de Andrade, Mariza, Kullo, Iftikhar, Li, Rongling, Mirel, Daniel, Crenshaw, Andrew, Bowen, James D., Li, Ge, Tsuang, Debby, McCurry, Susan, Teri, Linda, Larson, Eric B., Jarvik, Gail P., Carlson, Chris S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677889/
https://ncbi.nlm.nih.gov/pubmed/23762230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063481
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