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HDAC Inhibition Elicits Myocardial Protective Effect through Modulation of MKK3/Akt-1

We and others have demonstrated that HDAC inhibition protects the heart against myocardial injury. It is known that Akt-1 and MAP kinase play an essential role in modulation of myocardial protection and cardiac preconditioning. Our recent observations have shown that Akt-1 was activated in post-myoc...

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Detalhes bibliográficos
Main Authors: Zhao, Ting C., Du, Jianfeng, Zhuang, Shugang, Liu, Paul, Zhang, Ling X.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677871/
https://ncbi.nlm.nih.gov/pubmed/23762381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065474
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