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The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro.

The sequence AAUAAA is found near the polyadenylation site of eucaryotic mRNAs. This sequence is required for accurate and efficient cleavage and polyadenylation of pre-mRNAs in vivo. In this study we show that synthetic simian virus 40 late pre-mRNAs are cleaved and polyadenylated in vitro in a HeL...

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Udgivet i:Mol Cell Biol
Principais autores: Zarkower, D, Stephenson, P, Sheets, M, Wickens, M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367784/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.7.2317-2323.1986
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