Variant of TREM2 Associated with the Risk of Alzheimer’s Disease

BACKGROUND: Sequence variants, including the ε4 allele of apolipoprotein E, have been associated with the risk of the common late-onset form of Alzheimer’s disease. Few rare variants affecting the risk of late-onset Alzheimer’s disease have been found. METHODS: We obtained the genome sequences of 22...

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Detalhes bibliográficos
Principais autores: Jonsson, Thorlakur, Stefansson, Hreinn, Steinberg, Stacy, Jonsdottir, Ingileif, Jonsson, Palmi V., Snaedal, Jon, Bjornsson, Sigurbjorn, Huttenlocher, Johanna, Levey, Allan I., Lah, James J., Rujescu, Dan, Hampel, Harald, Giegling, Ina, Andreassen, Ole A., Engedal, Knut, Ulstein, Ingun, Djurovic, Srdjan, Ibrahim-Verbaas, Carla, Hofman, Albert, Ikram, M. Arfan, van Duijn, Cornelia M, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677583/
https://ncbi.nlm.nih.gov/pubmed/23150908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1211103
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