Role of Mutant CFTR in Hypersusceptibility of Cystic Fibrosis Patients to Lung Infections

Cystic fibrosis (CF) patients are hypersusceptible to chronic Pseudomonas aeruginosa lung infections. Cultured human airway epithelial cells expressing the ΔF508 allele of the cystic fibrosis transmembrane conductance regulator (CFTR) were defective in uptake of P. aeruginosa compared with cells exp...

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Bibliografiska uppgifter
Huvudupphovsmän: Pier, Gerald B., Grout, Martha, Zaidi, Tanweer S., Olsen, John C., Johnson, Larry G., Yankaskas, James R., Goldberg, Joanna B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677515/
https://ncbi.nlm.nih.gov/pubmed/8539601
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