Phase 1/2 Open-label Dose-escalation Study of Plasmid DNA Expressing Two Isoforms of Hepatocyte Growth Factor in Patients With Painful Diabetic Peripheral Neuropathy

This study aimed to evaluate the safety and preliminary efficacy of intramuscular injections of plasmid DNA (VM202) expressing two isoforms of hepatocyte growth factor (HGF) in subjects with painful diabetic peripheral neuropathy (PDPN). Twelve patients in three cohorts (4, 8, and 16 mg) received tw...

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Detaylı Bibliyografya
Asıl Yazarlar: Ajroud-Driss, Senda, Christiansen, Mark, Allen, Jeffrey A, Kessler, John A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677315/
https://ncbi.nlm.nih.gov/pubmed/23609019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.69
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