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Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells

Transfer RNAs (tRNAs) are typically considered housekeeping products with little regulatory function. However, several studies over the past 10 years have linked tRNA misregulation to cancer. We have previously reported that tRNA levels are significantly elevated in breast cancer and multiple myelom...

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Detaylı Bibliyografya
Asıl Yazarlar: Pavon-Eternod, Mariana, Gomes, Suzana, Rosner, Marsha R., Pan, Tao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677255/
https://ncbi.nlm.nih.gov/pubmed/23431330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.037507.112
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