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Distinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydro-sphingosine 1-phosphate in human neural progenitor cells

In vivo and in vitro studies suggest a crucial role for Sphingosine 1-phosphate (S1P) and its receptors in the development of the nervous system. Dihydrosphingosine 1-phosphate (dhS1P), a reduced form of S1P, is an agonist at S1P receptors, but the pharmacology and physiology of dhS1P has not been w...

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Detalhes bibliográficos
Main Authors: Callihan, Phillip, Zitomer, Nicholas C., Stoeling, Michael V., Kennedy, Perry C., Lynch, Kevin R., Riley, Ronald T., Hooks, Shelley B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677231/
https://ncbi.nlm.nih.gov/pubmed/22016110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.10.005
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