A Novel Anti-HIV Active Integrase Inhibitor with a Favorable In Vitro Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Metabolism Profile

Research efforts on the human immunodeficiency virus (HIV) integrase have resulted in two approved drugs. However, co-infection of HIV with Mycobacterium tuberculosis and other microbial and viral agents has introduced added complications to this pandemic, requiring favorable drug-drug interaction p...

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Autori principali: Okello, Maurice O., Mishra, Sanjay, Nishonov, Malik, Mankowski, Marie K., Russell, Julie D., Wei, Jiayi, Hogan, Priscilla A., Ptak, Roger G., Nair, Vasu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677213/
https://ncbi.nlm.nih.gov/pubmed/23602851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.04.005
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