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Saccharomyces cerevisiae secretes and correctly processes human interferon hybrid proteins containing yeast invertase signal peptides.

Synthetic oligonucleotides coding for the yeast invertase secretion signal peptide were fused to the gene for the mature form of human interferon (huIFN-alpha 2). Two plasmids (E3 and F2) were constructed. E3 contained the invertase signal codons in a reading frame with the mature huIFN-alpha 2 gene...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Chang, C N, Matteucci, M, Perry, L J, Wulf, J J, Chen, C Y, Hitzeman, R A
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1986
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023906/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.5.1812-1819.1986
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