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Saccharomyces cerevisiae secretes and correctly processes human interferon hybrid proteins containing yeast invertase signal peptides.

Synthetic oligonucleotides coding for the yeast invertase secretion signal peptide were fused to the gene for the mature form of human interferon (huIFN-alpha 2). Two plasmids (E3 and F2) were constructed. E3 contained the invertase signal codons in a reading frame with the mature huIFN-alpha 2 gene...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Chang, C N, Matteucci, M, Perry, L J, Wulf, J J, Chen, C Y, Hitzeman, R A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 1986
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3023906/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.5.1812-1819.1986
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