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Micropatterned Surfaces Functionalized with Electroactive Peptides for Detecting Protease Release from Cells

Matrix metalloproteinases (MMPs) regulate composition of extracellular matrix and play a critical role in cancer, fibrosis and wound healing. This paper describes a novel peptide based electrochemical biosensor for detecting activity of cell-secreted protease MMP9. In this sensing strategy, a peptid...

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Detalhes bibliográficos
Main Authors: Shin, Dong-Sik, Liu, Ying, Gao, Yandong, Kwa, Timothy, Matharu, Zimple, Revzin, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677045/
https://ncbi.nlm.nih.gov/pubmed/23181468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac302547p
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