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Micropatterned Sensing Hydrogels Integrated with Reconfigurable Microfluidics for Detecting Protease Release from Cells

Matrix metalloproteinases (MMPs) play a central role in the breakdown of the extracellular matrix and are typically upregulated in cancer cells. The goal of the present study is to develop microwells suitable for capture of cells and detection of cell-secreted proteases. Hydrogel microwells comprise...

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Dettagli Bibliografici
Pubblicato in:Anal Chem
Autori principali: Son, Kyung Jin, Shin, Dong-Sik, Kwa, Timothy, Gao, Yandong, Revzin, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370905/
https://ncbi.nlm.nih.gov/pubmed/24255999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402660z
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