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Immunological Reaction in TNF-α-Mediated Osteoclast Formation and Bone Resorption In Vitro and In Vivo

Tumor necrosis factor-α (TNF-α) is a cytokine produced by monocytes, macrophages, and T cells and is induced by pathogens, endotoxins, or related substances. TNF-α may play a key role in bone metabolism and is important in inflammatory bone diseases such as rheumatoid arthritis. Cells directly invol...

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Bibliografiske detaljer
Main Authors: Kitaura, Hideki, Kimura, Keisuke, Ishida, Masahiko, Kohara, Haruka, Yoshimatsu, Masako, Takano-Yamamoto, Teruko
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676982/
https://ncbi.nlm.nih.gov/pubmed/23762085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/181849
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