Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line.

Multidrug-resistant cells are cross-resistant to a wide range of unrelated drugs, many of which are used in cancer chemotherapy. We constructed a cDNA library from RNA of the multidrug-resistant Chinese hamster ovary cell line CHRC5. By differential screening we isolated cDNAs derived from mRNAs tha...

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Autori principali: Van der Bliek, A M, Van der Velde-Koerts, T, Ling, V, Borst, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC367694/
https://ncbi.nlm.nih.gov/pubmed/2431283
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