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miR-34a and the cardiomyopathy of senescence: SALT PNUTS, SALT PNUTS!
The search for eternal youth is as old as mankind. In a recent Nature paper, Boon et al find that miR34 and its mRNA target PNUTS mediate DNA damage repair and provoke cardiac senescence. Interrupting the miR-34a/PNUTS pathway promises to favorably modify age- and stress-induced cardiac degeneration...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3676894/ https://ncbi.nlm.nih.gov/pubmed/23663732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.04.004 |
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