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Sleep quality and preclinical Alzheimer Disease

OBJECTIVE: Sleep and circadian problems are very common in Alzheimer Disease (AD). Recent animal studies suggest a bidirectional relationship between sleep and amyloid-β (Aβ), a key molecule involved in AD pathogenesis. This study tested whether Aβ deposition in preclinical AD, prior to the appearan...

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Detalhes bibliográficos
Main Authors: Ju, Yo-El S., McLeland, Jennifer S., Toedebusch, Cristina D., Xiong, Chengjie, Fagan, Anne M, Duntley, Stephen P., Morris, John C., Holtzman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676720/
https://ncbi.nlm.nih.gov/pubmed/23479184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.2334
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