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Endothelial dysfunction in the regulation of portal hypertension

Portal hypertension is caused by an increased intrahepatic resistance, a major consequence of cirrhosis. Endothelial dysfunction in liver sinusoidal endothelial cells (LSECs) decreases the production of vasodilators, such as nitric oxide (NO) and favors vasoconstriction. This contributes to an incre...

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Bibliographic Details
Main Author: Iwakiri, Yasuko
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676636/
https://ncbi.nlm.nih.gov/pubmed/21745318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2011.02579.x
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