The volatile anesthetic isoflurane induces ecto-5′-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury

The volatile anesthetic isoflurane protects against renal ischemia and reperfusion injury by releasing renal tubular TGF-β1. Since adenosine is a powerful cytoprotective molecule, we tested whether TGF-β1 generated by isoflurane induces renal tubular ecto-5′-nucleotidase (CD73) and adenosine to prot...

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Bibliographic Details
Main Authors: Kim, Mihwa, Ham, Ahrom, Kim, Joo Yun, Brown, Kevin M., D’Agati, Vivette D., Lee, H. Thomas
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676468/
https://ncbi.nlm.nih.gov/pubmed/23423261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.43
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