Thyroid Hormone Reverses Aging-Induced Myocardial Fatty Acid Oxidation Defects and Improves the Response to Acutely Increased Afterload

BACKGROUND: Subclinical hypothyroidism occurs during aging in humans and mice and may contribute to the development of heart failure. Aging also impairs myocardial fatty acid oxidation, causing increased reliance on flux through pyruvate dehydrogenase (PDH) to maintain function. We hypothesize that...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ledee, Dolena, Portman, Michael A., Kajimoto, Masaki, Isern, Nancy, Olson, Aaron K.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676337/
https://ncbi.nlm.nih.gov/pubmed/23762386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065532
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars