TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy

A significant number of prostate cancers have been shown to have recurrent chromosomal rearrangements resulting in the fusion of the androgen regulated TMPRSS2 promoter to a member of the ETS transcription factor family, most commonly ERG. This results in ERG overexpression which may have a direct c...

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Autores principales: Gopalan, Anuradha, Leversha, Margaret A., Satagopan, Jaya M., Zhou, Qin, Al-Ahmadie, Hikmat A., Fine, Samson W., Eastham, James A., Scardino, Peter T., Scher, Howard I., Tickoo, Satish K., Reuter, Victor E., Gerald, William L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676271/
https://ncbi.nlm.nih.gov/pubmed/19190343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2467
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