TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high grade morphologic features

TMPRSS2-ERG gene rearrangement is seen in about half of clinically-localized prostate cancers, yet controversy exists regarding its prognostic implications. Similarly, the relationship of TMPRSS2-ERG fusion to Gleason score and morphology remains uncertain. We assigned Gleason scores and recorded mo...

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Hlavní autoři: Fine, Samson W., Gopalan, Anuradha, Leversha, Margaret A., Al-Ahmadie, Hikmat A., Tickoo, Satish K., Zhou, Qin, Satagopan, Jaya M., Scardino, Peter T., Gerald, William L., Reuter, Victor E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413944/
https://ncbi.nlm.nih.gov/pubmed/20562851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.120
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