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Protein oxidative modifications in the aging brain: consequence for the onset of neurodegenerative disease

The free radical theory of aging proposes the accumulation of altered, less active and toxic molecules of DNA, RNA, proteins and lipids caused by reactive oxygen species and reactive nitrogen species. Neurodegenerative disorders are characterized by an abnormal accumulation of oxidatively damaged ma...

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Detalhes bibliográficos
Main Authors: Grimm, Stefanie, Hoehn, Annika, Davies, Kelvin J., Grune, Tilman
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675897/
https://ncbi.nlm.nih.gov/pubmed/20815785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2010.512040
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