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Development of a high throughput screening assay for inhibitors of small ubiquitin-like modifier proteases

Small ubiquitin-like modifier (SUMO1-3) is a small group of proteins that are ligated to lysine residues in target proteins. SUMO conjugation is a highly dynamic process, as SUMOylated proteins are rapidly deconjugated by SUMO proteases. SUMO conjugation/deconjugation plays pivotal roles in major ce...

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Detalhes bibliográficos
Main Authors: Yang, Wei, Wang, Liangli, Paschen, Wulf
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675783/
https://ncbi.nlm.nih.gov/pubmed/23470489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113479971
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