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Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59

Pore-forming proteins containing the structurally conserved membrane attack complex/perforin fold play an important role in immunity and host-pathogen interactions. Intermedilysin (ILY) is an archetypal member of a cholesterol-dependent cytolysin subclass that hijacks the complement receptor CD59 to...

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Detalhes bibliográficos
Main Authors: Johnson, Steven, Brooks, Nicholas J., Smith, Richard A.G., Lea, Susan M., Bubeck, Doryen
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675674/
https://ncbi.nlm.nih.gov/pubmed/23665225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.029
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