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Mammalian iron metabolism and its control by iron regulatory proteins

Cellular iron homeostasis is maintained by iron regulatory proteins 1 and 2 (IRP1 and IRP2). IRPs bind to iron-responsive elements (IREs) located in the untranslated regions of mRNAs encoding protein involved in iron uptake, storage, utilization and export. Over the past decade, significant progress...

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Detalhes bibliográficos
Main Authors: Anderson, Cole P., Shen, Lacy, Eisenstein, Richard S., Leibold, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675657/
https://ncbi.nlm.nih.gov/pubmed/22610083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.05.010
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