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Mammalian iron metabolism and its control by iron regulatory proteins
Cellular iron homeostasis is maintained by iron regulatory proteins 1 and 2 (IRP1 and IRP2). IRPs bind to iron-responsive elements (IREs) located in the untranslated regions of mRNAs encoding protein involved in iron uptake, storage, utilization and export. Over the past decade, significant progress...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675657/ https://ncbi.nlm.nih.gov/pubmed/22610083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.05.010 |
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