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Fingolimod—A Sphingosine-Like Molecule Inhibits Vesicle Mobility and Secretion in Astrocytes

In the brain, astrocytes signal to the neighboring cells by the release of chemical messengers (gliotransmitters) via regulated exocytosis. Recent studies uncovered a potential role of signaling lipids in modulation of exocytosis. Hence, we investigated whether sphingosine and the structural analog...

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Detalles Bibliográficos
Main Authors: Trkov, Saša, Stenovec, Matjaž, Kreft, Marko, Potokar, Maja, Parpura, Vladimir, Davletov, Bazbek, Zorec, Robert
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675637/
https://ncbi.nlm.nih.gov/pubmed/22639011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22361
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