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Presenilin PS1ΔE9 disrupts mobility of secretory organelles in rat astrocytes
AIM: Alzheimer disease (AD) is largely considered a neuron-derived insult, but also involves failure of astroglia. A recent study indicated that mutated presenilin 1 (PS1M146V), a putative endoplasmic reticulum (ER) Ca(2+) channel with decreased Ca(2+) conductance, impairs the traffic of astroglial...
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| Publicado no: | Acta Physiol (Oxf) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5945314/ https://ncbi.nlm.nih.gov/pubmed/29392878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13046 |
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