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Detection of UV purine photoproducts in a defined sequence of human DNA.

The UV-irradiated, 3'-end-labeled, 92-base-pair terminus of the human alphoid sequence was incubated with purified endonuclease v. Previously unreported photoproducts were incised at purine loci. These were not pyrimidine photodimers, 6-4'-(pyrimidin-2'-one)-pyrimidines, base loss sit...

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Autors principals: Gallagher, P E, Duker, N J
Format: Artigo
Idioma:Inglês
Publicat: 1986
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC367562/
https://ncbi.nlm.nih.gov/pubmed/3785156
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